Heart safety check for new schizophrenia drug
NCT ID NCT05893862
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study checked whether a high dose of the experimental drug MK-8189 (elpipodect) affects heart rhythm in people with schizophrenia. 107 participants received the drug, a placebo, and an active control in a crossover design. The main goal was to see if the drug causes a dangerous heart rhythm change called QTc prolongation. This was a Phase 1 safety study, not a treatment trial.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for SCHIZOPHRENIA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
California Clinical Trials Medical Group managed by PAREXEL-PAREXEL International ( Site 0003)
Glendale, California, 91206, United States
-
Hassman Research Institute Marlton Site ( Site 0001)
Marlton, New Jersey, 08053, United States
-
NRC Research Institute ( Site 0004)
Orange, California, 92868, United States
-
Velocity Clinical Research, Hallandale Beach ( Site 0002)
Hallandale, Florida, 33009, United States