Heart safety check for new schizophrenia drug

NCT ID NCT05893862

First seen May 01, 2026 · Last updated May 15, 2026 · Updated 4 times

Summary

This study checked whether a high dose of the experimental drug MK-8189 (elpipodect) causes heart rhythm changes in people with schizophrenia. 107 participants received the drug, a placebo, and an active control in a crossover design. The main goal was to see if the drug's effect on heart rhythm was small enough to be considered safe.

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Contacts and locations

Locations

  • California Clinical Trials Medical Group managed by PAREXEL-PAREXEL International ( Site 0003)

    Glendale, California, 91206, United States

  • Hassman Research Institute Marlton Site ( Site 0001)

    Marlton, New Jersey, 08053, United States

  • NRC Research Institute ( Site 0004)

    Orange, California, 92868, United States

  • Velocity Clinical Research, Hallandale Beach ( Site 0002)

    Hallandale, Florida, 33009, United States

Conditions

Explore the condition pages connected to this study.