First human test of experimental cancer drug shows early safety profile

NCT ID NCT06894771

Summary

This early-stage study tested the safety of a new cancer drug called MK-4700, both alone and combined with an existing immunotherapy (pembrolizumab). The trial involved just 5 people with advanced solid tumors that had stopped responding to standard treatments. Researchers measured how the drug moved through the body and looked for safe dosage levels for future studies.

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Contacts and locations

Locations

  • Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 0102)

    Québec, Quebec, G1J 1Z4, Canada

  • John Theurer Cancer Center at Hackensack University Medical Center ( Site 0301)

    Hackensack, New Jersey, 07601, United States

  • NEXT Oncology ( Site 0300)

    San Antonio, Texas, 78229, United States

  • Princess Margaret Cancer Center ( Site 0101)

    Toronto, Ontario, M5G 2M9, Canada

  • Rabin Medical Center ( Site 0202)

    Petah Tikva, 4941492, Israel

  • Rambam Health Care Campus ( Site 0201)

    Haifa, 3109601, Israel

  • Sheba Medical Center ( Site 0200)

    Ramat Gan, 5265601, Israel

Conditions

Explore the condition pages connected to this study.