Liver study reveals how body handles new drug

NCT ID NCT07049939

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 23 times

Summary

This study looked at how the drug bomedemstat (MK-3543) moves through the body in people with mild or moderate liver problems compared to healthy volunteers. Nine participants received a single dose, and researchers measured drug levels in the blood. The goal was to understand if liver impairment changes how the drug is processed, which helps guide safe dosing.

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Contacts and locations

Locations

  • Orlando Clinical Research Center ( Site 0001)

    Orlando, Florida, 32809, United States

  • The Texas Liver Institute ( Site 0002)

    San Antonio, Texas, 78215, United States

  • University of Miami ( Site 0003)

    Miami, Florida, 33136, United States

Conditions

Explore the condition pages connected to this study.