New pill shows promise for tough blood cancers in early trial

NCT ID NCT05347225

First seen May 12, 2026 · Last updated May 15, 2026 · Updated 2 times

Summary

This early-stage study tests an oral drug called MK-1026 (nemtabrutinib) in 12 Chinese adults with blood cancers like lymphoma or leukemia that have returned or stopped responding to standard treatments. The main goals are to check the drug's safety, how the body processes it, and whether it can shrink tumors. Participants must have tried up to 4 prior therapies and cannot be candidates for other standard options.

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Contacts and locations

Locations

  • Guangdong Provincial People's Hospital-hematology department ( Site 1002)

    Guangzhou, Guangdong, 510080, China

  • Henan Cancer Hospital-hematology department ( Site 1003)

    Zhengzhou, Henan, 450008, China

  • Hunan Cancer Hospital ( Site 1004)

    Changsha, Hunan, 410013, China

  • Institute of hematology&blood disease hospital-Hematology ( Site 1001)

    Tianjin, Tianjin Municipality, 301636, China

  • SUN YAT-SEN UNIVERSITY CANCER CENTRE-Internal medicine ( Site 1007)

    Guangzhou, Guangdong, 511400, China

Conditions

Explore the condition pages connected to this study.