New study: keyhole valve fix may spare heart patients from second Open-Heart surgery

NCT ID NCT04402931

First seen Oct 01, 2025 · Last updated May 01, 2026 · Updated 25 times

Summary

This study compared two ways to treat a failed mitral heart valve: a newer, less invasive procedure (valve-in-valve) versus repeat open-heart surgery. Researchers followed 150 adults with severe valve problems to see which approach caused fewer major complications like death or stroke. The goal was to find out if the less invasive option is as safe and effective as surgery in the medium to long term.

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Contacts and locations

Locations

  • Hospital Ana Nery

    Salvador, Estado de Bahia, 41745900, Brazil

  • Hospital de Messejana Dr. Carlos Alberto Studart Gomes

    Fortaleza, Ceará, 60840285, Brazil

  • Instituto Dante Pazzanese de Cardiologia

    São Paulo, São Paulo, 04012909, Brazil

  • Instituto Nacional de Cardiologia

    Rio de Janeiro, Rio de Janeiro, 22240006, Brazil

  • Instituto de Cardiologia de Santa Catarina

    São José, Santa Catarina, 88103901, Brazil

  • Instituto do Coração (INCOR)

    São Paulo, São Paulo, 05403900, Brazil

  • UNIFESP

    São Paulo, São Paulo, 04021001, Brazil

Conditions

Explore the condition pages connected to this study.