Could a mitral valve fix a tricuspid problem? small trial tests donor tissue swap

NCT ID NCT06196684

Ongoing Disease control Sponsor: Chelyabinsk Regional Clinical Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a donated mitral valve can safely replace a diseased tricuspid valve in 30 patients with primary tricuspid valve disease. The goal is to see if this approach is safe and works well in the short term. Researchers will track complications like bleeding, stroke, and valve function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: mitral valve allograft (donor tissue)
What this could lead to: If successful, this could offer a new surgical option for tricuspid valve replacement using donor tissue, potentially improving outcomes.
What could go wrong: This is a very small, early-stage study with only 30 participants, so results may not apply widely. Risks include bleeding, infection, and valve dysfunction.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

tricuspid valve disorder tricuspid valve insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALLOGRAFTS TRICUSPID VALVE INSUFFICIENCY

Contacts and locations

Locations

Department of Cardiac Surgery

Chelyabinsk, Chelyabinsk Oblast, 454076, Russia

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