Heart valve repair showdown: clip vs. scalpel

NCT ID NCT04198870

Ongoing Disease control Sponsor: Abbott Medical Devices Source: ClinicalTrials.gov ↗

Summary

This study compares two procedures for fixing a severely leaking mitral heart valve in patients at moderate surgical risk. It tests whether a less invasive device called MitraClip works as well as traditional open-heart surgery repair. Researchers will track 500 participants for two years to see which approach leads to better survival, fewer complications, and improved quality of life.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Abbott Northwestern Hospital

Minneapolis, Minnesota, 55407, United States
Albany Medical Center

Albany, New York, 12208, United States
Allegheny General Hospital - ASRI

Pittsburgh, Pennsylvania, 15212, United States
Arizona Cardiovascular Research Center

Phoenix, Arizona, 85016, United States
Ascension Saint Thomas

Nashville, Tennessee, 37205, United States
Ascension St. Vincent

Indianapolis, Indiana, 46240, United States
Ascension Texas Cardiovascular Research

Austin, Texas, 78705, United States
Banner-University Medical Center Phoenix

Phoenix, Arizona, 85006, United States
Baptist Medical Center

Jacksonville, Florida, 32207, United States
Beaumont Hospital, Royal Oak

Royal Oak, Michigan, 48073, United States
Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States
Cardiology Associates of Mobile, Inc.

Mobile, Alabama, 36608, United States
Cardiovascular Research Institute of Kansas

Wichita, Kansas, 67226, United States
Carolinas Medical Center

Charlotte, North Carolina, 28203, United States
Center Inselspital Bern

Bern, Canton of Bern, 3010, Switzerland
Christ Hospital

Cincinnati, Ohio, 45219, United States
Cooper University Hospital

Camden, New Jersey, 08103, United States
Deutsches Herzzentrum München des Freistaates Bayern

München, 80636, Germany
Duke University Medical Center

Durham, North Carolina, 27705, United States
HCA Houston Healthcare Medical Center

Houston, Texas, 77004, United States
Henry Ford Health

Detroit, Michigan, 48202, United States
Herz-und Diabetes Zentrum NRW

Bad Oeynhausen, North Rhine-Westphalia, 32545, Germany
Houston Methodist

Houston, Texas, 77030, United States
Institut de Cardiologie de Montreal (Montreal Heart Inst.)

Montreal, Quebec, H1T 1C8, Canada
Integris Baptist Medical Center

Oklahoma City, Oklahoma, 73112, United States
Intermountain Medical Center

Murray, Utah, 84157, United States
Jersey Shore University Medical Center

Neptune City, New Jersey, 07753, United States
Kansas University Medical Center

Kansas City, Kansas, 66160, United States
Klinikum der Johann Wolfgang Goethe-Universität Frankfurt

Frankfurt am Main, Hesse, 60590, Germany
Lankenau Institute for Medical Research

Wynnewood, Pennsylvania, 19096, United States
Los Robles Regional Medical Center

Thousand Oaks, California, 91360, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
Mercy General Hospital

Sacramento, California, 95819, United States
Mission Health & Hospitals

Asheville, North Carolina, 28801, United States
Morristown Medical Center

Morristown, New Jersey, 07962, United States
Mt. Carmel East

Columbus, Ohio, 43213, United States
NCH Healthcare System

Naples, Florida, 34102, United States
NYU Langone Health

New York, New York, 10016, United States
New York-Presbyterian/Columbia University Medical Center

New York, New York, 10032, United States
Northwestern Memorial Hospital

Chicago, Illinois, 60611, United States
Piedmont Heart Institute

Atlanta, Georgia, 30309, United States
Pinnacle Health Cardiovascular Institute, Inc.

Harrisburg, Pennsylvania, 17105, United States
Prairie Education & Research Cooperative

Springfield, Illinois, 62701, United States
Rochester Regional Health

Rochester, New York, 14617, United States
Saint Joseph Hospital

Denver, Colorado, 80218, United States
Scripps Health

La Jolla, California, 92037, United States
Sentara Norfolk General Hospital

Norfolk, Virginia, 23507, United States
South Shore University Hospital

Bay Shore, New York, 11706, United States
St. Francis Hospital

Roslyn, New York, 11576, United States
St. Josephs Hospital and Medical Center

Phoenix, Arizona, 85013, United States
St. Michael's Hospital

Toronto, Ontario, M5B 1W8, Canada
Stanford University Medical Center

Stanford, California, 94305, United States
Sunnybrook Health Sciences Centre

Toronto, Ontario, M5N 3M5, Canada
Sutter Medical Center, Sacramento

Sacramento, California, 95816, United States
Swedish Medical Center

Seattle, Washington, 98107, United States
The Heart Institute at Virginia Mason

Seattle, Washington, 98111, United States
Toronto General Hospital

Toronto, Ontario, M5G 2C4, Canada
TriStar Centennial Medical Center

Nashville, Tennessee, 37203, United States
Tucson Medical Center

Tucson, Arizona, 85712, United States
UPMC

Pittsburgh, Pennsylvania, 15213, United States
UTHealth Memorial Hermann

Houston, Texas, 77008, United States
University Hospital - Univ. of Alabama at Birmingham (UAB)

Birmingham, Alabama, 35249, United States
University Hospitals Cleveland Medical Center

Cleveland, Ohio, 44106, United States
University of California - Davis Medical Center

Sacramento, California, 95817, United States
University of California at San Francisco

San Francisco, California, 94143, United States
University of Michigan Medical Center

Ann Arbor, Michigan, 48104, United States
University of Virginia Medical Center

Charlottesville, Virginia, 22908, United States
Universitätsklinikum Rostock (AöR)

Rostock, 18057, Germany
Universitätsklinikum Ulm

Ulm, Bad-wur, 89081, Germany
Universitätsmedizin der Johannes Gutenberg-Universität Mainz

Mainz, Rhinela, 55131, Germany
Vanderbilt Heart & Vascular Institute

Nashville, Tennessee, 37232, United States
Via Christi Regional Medical Center - St. Francis Campus

Wichita, Kansas, 67214, United States
West Virginia University Hospital

Morgantown, West Virginia, 26506, United States
Yale New Haven Hospital

New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.

MITRAL VALVE REGURGITATION