Blood and skin samples could unlock new mitochondrial disease treatments

NCT ID NCT06474104

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study collects blood and skin samples from 100 people with primary mitochondrial diseases and healthy volunteers aged 3 to 85. Researchers will study how different mitochondrial mutations affect cell function and look for biomarkers. The samples will also help test a new therapy called mitochondrial augmentation technology (MAT).

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could help researchers develop a new therapy called mitochondrial augmentation technology (MAT) for mitochondrial diseases.
What could go wrong
This is an early-stage sample collection study, not a treatment trial. It may not lead to an effective therapy, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sheba Medical Center - Tel Ashomer

    RECRUITING

    Ramat Gan, Israel, 5266202, Israel