Sickle cell drug study looks under the microscope at red blood cells

NCT ID NCT05675436

First seen Nov 01, 2025 · Last updated May 11, 2026 · Updated 25 times

Summary

This observational study looks at how the drug mitapivat changes red blood cells in people with sickle cell disease. Researchers will measure how well the cells carry oxygen and how long they survive. The study involves about 6 people already enrolled in a larger trial, with extra blood draws and a non-invasive skin test. The goal is to understand the drug's effects, not to provide direct treatment.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.