Which route for misoprostol best cuts bleeding in C-Sections?

NCT ID NCT07728084

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This trial tests whether giving misoprostol into the uterus or through the rectum better reduces blood loss during and after planned cesarean delivery. One hundred forty low-risk pregnant women will receive the drug by one of these two routes. The goal is to find the most effective way to prevent postpartum hemorrhage, a leading cause of maternal complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
misoprostol tablets given either rectally or into the uterus
What this could lead to
If one method works better, it could lead to a safer, simpler way to prevent dangerous bleeding after cesarean delivery.
What could go wrong
This is a small, single-center trial, so results may not apply to all women. Both routes can cause side effects like shivering or fever.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cairo University

    Cairo, Cairo Governorate, 12111, Egypt