Could an old depression drug help girls with rett syndrome?
NCT ID NCT07430046
First seen Feb 25, 2026 · Last updated Apr 25, 2026 · Updated 8 times
Summary
This study tests whether mirtazapine, an antidepressant, can improve motor skills, mood, and sleep in girls and women with Rett syndrome, a rare genetic disorder. Fifty-four participants aged 5 to 40 will receive the drug for six months. The goal is to see if it reduces symptoms like hand movement problems and anxiety.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Centro Epilessia - Unità Neurologia Pediatrica, ASST Ospedale Santi Carlo Paolo - Dipartimento Scienze della Salute, Università di Milano
RECRUITINGMilan, 20142, Italy
Contact
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UOC di Neuropsichiatria Infantile, Policlinico Universitario "Gaetano Martino" di Messina, University of Messina. Messina
RECRUITINGMessina, 98125, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Unità di Neuropsichiatria Infantile, IRCCS, Istituto Giannina Gaslini, Genova
RECRUITINGGenova, 16147, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Unità di Pediatria, Dipartimento della Donna e dei Bambini - Policlinico S. M. alle Scotte. Siena
RECRUITINGSiena, 53100, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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