Minoxidil shows promise for reversing gray hair in new study
NCT ID NCT06813963
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed Phase 4 trial tested whether applying minoxidil (5%) to the scalp twice daily for 12 months could restore color to gray hair in adults aged 18 to 65 with non-medical graying. Researchers compared 141 participants using minoxidil versus a placebo, measuring changes in a gray hair severity scale. The goal was to see if this common hair-loss drug could also repigment hair, offering a potential alternative to dyes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
minoxidil (5% topical solution)
What this could lead to
If it works, this could point toward a simple over-the-counter treatment to reverse gray hair without dye.
What could go wrong
This is a small, completed Phase 4 trial. Results may not be generalizable, and minoxidil is not approved for repigmentation—side effects like scalp irritation are possible.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Nanfang Hospital, Southern Medical University
Guangzhou, Guangdong, 510515, China
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The First People's Hospital of Zhaoqing
Zhaoqing, Guangdong, 526060, China