Heart drug trial offers hope for critically ill newborns
NCT ID NCT02951130
Summary
This study tested whether a medication called milrinone, which helps the heart pump and relax, could improve oxygen levels in newborns with a severe birth defect called congenital diaphragmatic hernia (CDH). The trial involved 66 critically ill, full-term newborns who were struggling to breathe. Researchers gave some infants milrinone and others a placebo to see if the drug was safe and could help their lungs and heart work better.
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Contacts and locations
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Locations
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Brown University, Women & Infants Hospital of Rhode Island
Providence, Rhode Island, 02905, United States
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Case Western Reserve University, Rainbow Babies and Children's Hospital
Cleveland, Ohio, 44106, United States
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Children's Hospital of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Children's Mercy
Kansas City, Missouri, 64108, United States
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Cincinnati Children's Medical Center
Cincinnati, Ohio, 45267, United States
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Columbia University
New York, New York, 10032, United States
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Duke University
Durham, North Carolina, 27710, United States
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Emory University
Atlanta, Georgia, 30303, United States
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RTI International
Durham, North Carolina, 27709, United States
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Research Institute at Nationwide Children's Hospital
Columbus, Ohio, 43205, United States
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Stanford University
Palo Alto, California, 94304, United States
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University of Alabama at Birmingham
Birmingham, Alabama, 35233, United States
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University of Iowa
Iowa City, Iowa, 52242, United States
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University of New Mexico
Albuquerque, New Mexico, 87131, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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University of Rochester
Rochester, New York, 14642, United States
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University of Texas Health Science Center at Houston
Houston, Texas, 77030, United States
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University of Texas Southwestern Medical Center at Dallas
Dallas, Texas, 75235, United States
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University of Utah
Salt Lake City, Utah, 84108, United States
Conditions
Explore the condition pages connected to this study.