Gum regeneration showdown: microneedling with PRF vs hyaluronic acid

NCT ID NCT07280507

First seen Dec 18, 2025 · Last updated May 14, 2026 · Updated 22 times

Summary

This small early-phase trial tested two non-surgical methods to rebuild the small triangle of gum tissue between teeth (called the papilla) that can shrink due to gum disease or other causes. Seven adults with mild gum recession received both treatments in different areas of their mouth to compare results. The goal was to see if microneedling combined with a natural blood concentrate (i-PRF) works better than a standard hyaluronic acid gel injection for restoring gum height and width.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PAPILLA RECONSTRUCTION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • King AbdulAziz University

    Jeddah, Saudi Arabia

Conditions

Explore the condition pages connected to this study.