Tiny needle patch takes aim at skin cancer

NCT ID NCT05377905

First seen Jun 25, 2026 · Last updated Jun 25, 2026

Summary

This study tests a small adhesive patch with tiny needles that deliver a low dose of the chemotherapy drug doxorubicin directly into skin cancer tumors. It involves 48 people with squamous cell skin cancer who are either immune-competent or immune-suppressed. The goal is to see if the patch is safe and can clear the tumor under and around it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Pittsburgh Medical Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

doxorubicin delivered via a microneedle patch

What this could lead to

If it works, this could offer a less invasive, targeted treatment for skin cancer that avoids systemic chemo side effects.

What could go wrong

This is an early-phase trial with only 48 participants, so results may not apply broadly. The patch only treats the area under it, and cancer may still recur elsewhere.

Conditions

The condition(s) this trial relates to.

skin squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.