Early-Stage lung cancer drug trial halted before results

NCT ID NCT05275868

First seen Nov 10, 2025 · Last updated Apr 28, 2026 · Updated 18 times

Summary

This early-phase study tested a new drug called MGY825 in 41 adults with advanced non-small cell lung cancer that had specific genetic changes. The main goal was to check the drug's safety and find the right dose. The study was stopped early, so we don't have full results on how well it worked.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Memorial Sloan Kettering

    New York, New York, 10017, United States

  • Memorial Sloan Kettering Onc. Dept

    New York, New York, 10017, United States

  • NYU School of Medicine

    New York, New York, 10015, United States

  • Novartis Investigative Site

    Frankfurt am Main, Hesse, 60590, Germany

  • Novartis Investigative Site

    Cologne, North Rhine-Westphalia, 50937, Germany

  • Novartis Investigative Site

    Essen, 45147, Germany

  • Novartis Investigative Site

    Chuo Ku, Tokyo, 104 0045, Japan

  • Novartis Investigative Site

    Seoul, 03080, South Korea

  • Novartis Investigative Site

    Madrid, 28050, Spain

  • Novartis Investigative Site

    Geneva, CH 1211, Switzerland

  • Novartis Investigative Site

    Sankt Gallen, 9007, Switzerland

  • Uni Of TX MD Anderson Cancer Cntr

    Houston, Texas, 77030, United States

  • Wash U School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.