Could a common drug boost brain function in seniors with 'Silent' stroke damage?
NCT ID NCT07700615
First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time
Summary
This study tests whether adding the drug Mexidol to standard care can improve thinking and memory in adults aged 75 and older who have mild cognitive issues due to poor blood flow in the brain, but not dementia. Participants receive Mexidol first as an IV infusion for 5 days, then as tablets for 60 days, or standard therapy alone. The main goal is to see if Mexidol leads to better scores on a common cognitive test.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Mexidol (ethylmethylhydroxypyridine succinate) given first as an IV infusion then as oral tablets
- What this could lead to
- If it works, this could point toward a treatment option for older adults with early vascular-related memory and thinking problems.
- What could go wrong
- This is a small, early-phase trial, so results may not be conclusive or apply to everyone. The drug is already approved for other uses, but its benefit for cognitive impairment is not yet proven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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City Hospital № 40 of Kurortny District
Saint Petersburg, 197706, Russia
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Ivanovo Regional Clinical Hospital
Ivanovo, 153040, Russia
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Medinet, LLC
Saint Petersburg, 197136, Russia
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Vsevolozhsk Clinical Interdistrict Hospital
Vsevolozhsk, 188643, Russia