Researchers track Body's response to lifesaving fat disorder drug

NCT ID NCT04026178

Summary

This study monitored 11 patients with generalized lipodystrophy, a rare disorder causing severe fat loss and metabolic problems, who were starting daily metreleptin injections. The main goal was to see if their immune systems developed antibodies against the drug over three years and to check for any related safety issues. This was a required follow-up study after the drug was approved to ensure its long-term safety profile.

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Contacts and locations

Locations

  • Childrens Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Endocrinology Research Associates

    Columbus, Ohio, 43201, United States

  • Ochsner Clinic

    New Orleans, Louisiana, 70121, United States

  • Ohio State University

    Columbus, Ohio, 43203, United States

  • Seattle Children's Hospital

    Seattle, Washington, 98105, United States

  • Univ. Alabama-Birmingham

    Birmingham, Alabama, 35294, United States

  • University Texas Southwestern INT

    Dallas, Texas, 75390, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

Conditions

Explore the condition pages connected to this study.