Electric current may boost Methotrexate's power against vitiligo
NCT ID NCT07208890
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two ways of delivering methotrexate to treat vitiligo patches: using a low-intensity electric current (iontophoresis) versus a standard gel. Thirty adults with stable vitiligo will be randomly assigned to one of the two treatments for 8 weeks. Researchers will measure how much skin color returns and track quality of life and liver safety.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- methotrexate
- What this could lead to
- If it works, this could offer a more effective, localized treatment for vitiligo with fewer side effects than oral methotrexate.
- What could go wrong
- This is a small, early pilot study with only 30 people, so results may not apply widely. The treatment may not cause significant repigmentation, and liver function must be monitored.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.