Common diabetes drug tested to protect against radiation side effects in thyroid cancer

NCT ID NCT03109847

First seen Dec 18, 2025 · Last updated May 13, 2026 · Updated 17 times

Summary

This small pilot study looked at whether metformin, a common diabetes medicine, could reduce side effects like dry mouth and taste changes caused by radioactive iodine treatment in people with thyroid cancer. The study planned to enroll 13 participants but was terminated early. The goal was to see if metformin could protect healthy tissues from radiation damage.

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Contacts and locations

Locations

  • Sidney Kimmel Cancer Center at Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

Conditions

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