Diabetes drug metformin could be new hope for veterans with leg pain

NCT ID NCT05132439

First seen Nov 01, 2025 · Last updated Jun 12, 2026 · Updated 33 times

Summary

This study tests whether metformin, a safe diabetes drug, can improve walking ability and reduce leg pain in 200 veterans with peripheral artery disease (PAD). Participants will take metformin or a placebo for several months. The goal is to see if metformin can reduce inflammation and improve blood flow to the legs, offering a new treatment option for this common condition.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA

    RECRUITING

    Pittsburgh, Pennsylvania, 15240, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.