Diabetes drug metformin could be new hope for leg pain sufferers

NCT ID NCT05132439

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 24 times

Summary

This study tests whether metformin, a safe diabetes drug, can improve walking ability and reduce leg pain in veterans with peripheral artery disease (PAD). PAD causes leg pain during activity due to blocked arteries, and there is no effective medical treatment. The trial will give metformin or a placebo to 200 veterans to see if it helps them walk farther and feel better.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA

    RECRUITING

    Pittsburgh, Pennsylvania, 15240, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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