Could a common diabetes drug boost brain power in schizophrenia?

NCT ID NCT05838573

First seen Jan 11, 2026 · Last updated May 06, 2026 · Updated 22 times

Summary

This study is testing whether metformin, a drug typically used for diabetes, can improve cognitive problems like memory and attention in people with schizophrenia. Researchers will give 120 participants either metformin or a placebo for 24 weeks and measure changes in thinking skills and brain scans. The goal is to find a new way to help with the cognitive symptoms of schizophrenia, which current treatments often don't address.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mental Health Institute of Second Xiangya Hospital,CSU

    RECRUITING

    Changsha, Hunan, 410011, China

    Contact Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shandong Mental Health Center

    RECRUITING

    Jinan, Shandong, 250014, China

    Contact Phone: •••-•••-••••

  • The Second People's Hospital of Dali Bai Autonomous Prefecture

    RECRUITING

    Dali, Yunnan, 671014, China

    Contact Phone: •••-•••-••••

  • The Third Peoples's Hospital of Jiangyin

    RECRUITING

    Jiangyin, Jiangsu, 214400, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.