Could a diabetes drug strengthen bone grafts in kids with clefts?
NCT ID NCT07536620
First seen Apr 30, 2026 · Last updated May 14, 2026 · Updated 2 times
Summary
This study tests whether adding metformin gel to a standard bone graft improves bone quality in children aged 8-12 with a cleft in the upper jaw (alveolar cleft). Half of the 36 participants will receive the metformin-enhanced graft; the other half will get a placebo. The goal is to see if the metformin helps the bone heal stronger and denser.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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