Massive study to uncover how obesity and diabetes speed up liver damage

NCT ID NCT07534046

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows over 4,300 adults with compensated advanced chronic liver disease to see how metabolic disorders like obesity, diabetes, and high cholesterol affect disease progression. Participants receive standard care and are monitored every 3 to 6 months for up to 5 years. No experimental treatments are given. The goal is to build a risk prediction model that could help personalize care and prevent serious complications like liver failure or cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to better ways to predict serious liver complications and identify new targets for treatment.

What could go wrong

This is an observational study, so it cannot prove cause and effect. Results may not apply to all populations, and the long follow-up may lead to dropouts.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

metabolic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.