Can targeted muscle techniques outperform standard therapy for piriformis pain?

NCT ID NCT07769203

First seen Aug 17, 2026 · Last updated Aug 17, 2026

Summary

This study tests whether two hands-on therapies—muscle energy technique and myofascial release—can improve pain, muscle strength, and activation in people with piriformis syndrome, a condition where a deep buttock muscle irritates the sciatic nerve. About 72 adults aged 18–65 with the condition will receive one of the techniques alongside conventional physical therapy for 8 weeks. Researchers will use objective tools like pressure sensors and electromyography to measure changes, aiming to identify which approach offers better relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Muscle Energy Technique and Myofascial Release Technique (manual therapy procedures)
What this could lead to
If one technique proves more effective, it could become a preferred non-drug treatment for piriformis syndrome, offering better pain relief and muscle function.
What could go wrong
This is a small, early-stage trial, so results may not apply to everyone. Manual therapy effects can vary, and the study doesn't compare against a placebo, so benefits might be partly due to attention or expectation.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hasan Kalyoncu University Faculty of Health Sciences

    Gaziantep, Şehitkamil, 27000, Turkey (Türkiye)

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