New combo therapy shows promise for rare lung cancer

NCT ID NCT03762018

First seen May 16, 2026 · Last updated May 16, 2026

Summary

This study tested whether adding the immunotherapy drug atezolizumab to standard treatment (bevacizumab plus chemotherapy) helps people with advanced malignant pleural mesothelioma live longer. The trial involved 400 adults whose cancer could not be removed by surgery. Researchers measured overall survival and how long the cancer stayed under control. This is a disease-control study, not a cure, because ongoing treatment is needed.

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Contacts and locations

Locations

  • AULSS2 Marca Trevigiana Treviso

    Treviso, Italy

  • Addenbrooke's Hospital

    Cambridge, United Kingdom

  • Alicante University Hospital ISABIAL

    Alicante, Spain

  • CHU Liege

    Liège, Belgium

  • CHUV

    Lausanne, Switzerland

  • Caen- CHU

    Caen, France

  • Clatterbridge Cancer Centre

    Liverpool, United Kingdom

  • Complexo Hospitalario Universitario de Vigo

    Vigo, Spain

  • Curie Cancer Center Paris

    Paris, France

  • Ferdinando Cerciello

    Bern, Switzerland

  • Fondazione IRCCS Istituto Nazionale die Tumori

    Milan, Italy

  • Guy's and St Thomas' Hospital

    London, United Kingdom

  • Hospital Nord

    Marseille, France

  • Hospital Parc Tauli Sabadell

    Sabadell, Spain

  • ICO Hospitalet

    Barcelona, Spain

  • IRCCS Instituto Tumori Giovanni Paolo II

    Bari, Italy

  • Instituto Europeo di Oncologia (IEO)

    Milan, Italy

  • Istituto Oncologica della Svizzera Italiana

    Bellinzona, Switzerland

  • Kantonsspital Aarau

    Aarau, Switzerland

  • Kantonsspital Graubünden

    Chur, Switzerland

  • Kantonsspital St. Gallen

    Sankt Gallen, Switzerland

  • Kantonsspital Winterthur

    Winterthur, Switzerland

  • Kent Oncology Centre

    Maidstone, United Kingdom

  • Le Mans - CHG

    Le Mans, France

  • Luzerner Kantonsspital

    Lucerne, Switzerland

  • Lyon - Centre Léon Bérard

    Lyon, France

  • Plymouth Hospitals NHS Trust

    Plymouth, United Kingdom

  • Puerta de Hierro Hospital

    Majadahonda, Spain

  • Royal Cornwall Hospital

    Truro, United Kingdom

  • Royal Marsden Hospital (Fulham Road)

    London, United Kingdom

  • Royal Marsden Hospital (Sutton)

    London, United Kingdom

  • SS Antonio e Biagio e Cesare Arrigo Hospital

    Alessandria, Italy

  • Toulouse - CHU

    Toulouse, France

  • Tours - CHU

    Tours, France

  • Unicancer - Institut Bergonie

    Bordeaux, France

  • University Hospital Leuven

    Leuven, Belgium

  • University Hospital of Turin

    Turin, Italy

  • UniversitätSpital Zürich

    Zurich, Switzerland

  • Vall Hebron University Hospital/Vall Hebron Institue Oncology

    Barcelona, Spain

  • Virgen del Rocio

    Seville, Spain

  • Weston Park Hospital

    Sheffield, United Kingdom

  • Wythenshawe Hospital

    Manchester, United Kingdom

Conditions

Explore the condition pages connected to this study.