Chemo first, then radiation: new hope for eye cancer patients

NCT ID NCT05893654

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 23 times

Summary

This early-stage trial tests whether giving chemotherapy directly into the eye's blood vessels can shrink large eye tumors enough for safer radiation treatment. Ten adults with thick choroidal melanoma will receive the drug melphalan, followed by a radioactive plaque placed on the eye. Researchers will monitor tumor size, vision, and retinal health over six months to see if this combination is safe and effective.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto - USP

    Ribeirão Preto, São Paulo, 14040-906, Brazil

Conditions

Explore the condition pages connected to this study.