Melatonin timing matters: study tests if earlier is better for sleep
NCT ID NCT07514507
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether taking melatonin earlier in the evening (3 hours before bed) or at a higher dose (4 mg) helps healthy adults fall asleep faster and sleep better. Fourteen participants will try different combinations of melatonin and placebo while their sleep is measured with brain wave monitoring. The goal is to find the most effective timing and dose for improving sleep.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Melatonin
What this could lead to
If it works, this could point toward better timing and dosing recommendations for melatonin to improve sleep in healthy people.
What could go wrong
This is a very small, early-stage study in healthy adults without sleep problems, so results may not apply to people with sleep disorders. The effects may be subtle or not meaningful in real life.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Pisa, Institute of Physiology, Sonnolab
Pisa, PI, 56126, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••