Melatonin may soothe agitation in kids after tonsil surgery

NCT ID NCT07375342

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving children melatonin before tonsillectomy surgery can reduce confusion and agitation when they wake up. About 120 children will receive either melatonin or a placebo 30 minutes before anesthesia. Researchers will measure agitation levels and recovery time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

melatonin

What this could lead to

If it works, this could offer a simple, low-cost way to help children wake up more calmly after tonsillectomy.

What could go wrong

This is a small, early-stage trial. Melatonin may not reduce agitation better than placebo, and some children may have side effects like drowsiness.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Psychomotor Agitation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Benha University Hospital

    Banhā, Egypt