New Virus-Based therapy enters final testing for Tough-to-Treat skin cancer

NCT ID NCT06264180

Recruiting now Disease control Sponsor: Replimune Inc. Source: ClinicalTrials.gov ↗

Summary

This study is for people with advanced melanoma that has continued to grow despite receiving two standard types of immunotherapy. It aims to see if a new treatment—a modified virus injected directly into tumors, combined with the drug nivolumab—works better and helps people live longer than the current standard treatments chosen by their doctor. About 400 participants will be randomly assigned to receive either the new combination or their physician's choice of therapy.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Advocate Lutheran General Hospital
WITHDRAWN

Park Ridge, Illinois, 60068, United States
Banner MD Anderson Cancer Center
RECRUITING

Gilbert, Arizona, 85234, United States

Contact
CHU Nice
RECRUITING

Nice, 06200, France

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CHU de Lille
RECRUITING

Lille, 59000, France

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Charité - Universitätsmedizin Berlin
RECRUITING

Berlin, 10117, Germany

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Clatterbridge Cancer Centre NHS Foundation Trust
RECRUITING

Liverpool, L7 8YA, United Kingdom

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Clinica Universidad de Navarra - Madrid
RECRUITING

Madrid, 28027, Spain

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Clinica Universidad de Navarra - Pamplona
RECRUITING

Pamplona, 31008, Spain

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Corewell Health
RECRUITING

Grand Rapids, Michigan, 49503, United States

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Dartmouth Hitchcock Cancer Center
RECRUITING

Lebanon, New Hampshire, 03756, United States

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Duke Cancer Center
RECRUITING

Durham, North Carolina, 27710, United States

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Fox Chase Cancer Center
RECRUITING

Philadelphia, Pennsylvania, 19111, United States

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Hackensack University Medical Center
RECRUITING

Hackensack, New Jersey, 07601, United States

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Helios Klinik
RECRUITING

Erfurt, 99089, Germany

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Henry Ford Cancer - Detroit (Brigitte Harris Cancer Pavilion)
RECRUITING

Detroit, Michigan, 48202, United States

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Hopital de La Timone
RECRUITING

Marseille, 13005, France

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Hospices Civils de Lyon (HCL) - Centre Hospitalier Lyon-Sud
RECRUITING

Pierre-Bénite, 69495, France

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Hospital Clinic de Barcelona
RECRUITING

Barcelona, 08036, Spain

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Hospital Clínico Universitario Virgen de la Arrixaca
RECRUITING

El Palmar, 30120, Spain

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Hospital Universitari Vall d'Hebron
RECRUITING

Barcelona, 08035, Spain

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Hospital Universitario 12 de Octubre
RECRUITING

Madrid, 28041, Spain

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Huntsman Cancer Institute
RECRUITING

Salt Lake City, Utah, 84112, United States

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Hôpital Saint Louis - AP-HP
RECRUITING

Paris, 75010, France

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Institut Gustave Roussy
RECRUITING

Villejuif, 94800, France

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Intermountain Health
RECRUITING

Murray, Utah, 84107, United States

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MD Anderson Cancer Center at Cooper
RECRUITING

Camden, New Jersey, 08103, United States

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Maria Sklodowska-Curie National Research Institute of Oncology
RECRUITING

Warsaw, 02-781, Poland

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MedStar Washington Hospital Center
RECRUITING

Washington D.C., District of Columbia, 20010, United States

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Memorial Cancer Institute at Memorial Regional Hospital
RECRUITING

Hollywood, Florida, 33021, United States

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Moffitt Cancer Center
RECRUITING

Tampa, Florida, 33612, United States

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Montefiore Medical Center
RECRUITING

The Bronx, New York, 10461, United States

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Morristown Medical Center - Atlantic Health System
RECRUITING

Morristown, New Jersey, 07960, United States

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Northwell Health, R.J. Zuckerberg Cancer Center
RECRUITING

Lake Success, New York, 11042, United States

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Northwestern Memorial Hospital
RECRUITING

Chicago, Illinois, 60611, United States

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Rhode Island Hospital
RECRUITING

Providence, Rhode Island, 02903, United States

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Roswell Park Cancer Institute
RECRUITING

Buffalo, New York, 14263, United States

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San Francisco Oncology Associates
RECRUITING

San Francisco, California, 94115, United States

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St. George Regional Hospital
RECRUITING

St. George, Utah, 84790, United States

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Stanford Cancer Institute
RECRUITING

Palo Alto, California, 94304, United States

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Stony Brook University Cancer Center
RECRUITING

Stony Brook, New York, 11794, United States

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Sutter Medical Group
RECRUITING

Sacramento, California, 95816, United States

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Texas Oncology
RECRUITING

Dallas, Texas, 75246, United States

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The Angeles Clinic and Research Institute
RECRUITING

Los Angeles, California, 90025, United States

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The Melanoma and Skin Cancer Institute
RECRUITING

Englewood, Colorado, 80113, United States

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The Ohio State University- Martha Morehouse Tower
RECRUITING

Columbus, Ohio, 43210, United States

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The Royal Marsden NHS Foundation Trust
RECRUITING

London, SW3 6JJ, United Kingdom

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The University of Texas MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States

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Thomas Jefferson University
RECRUITING

Philadelphia, Pennsylvania, 19107, United States

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UC Irvine Health, Chao Family Comprehensive Cancer Center
RECRUITING

Orange, California, 92868, United States

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UC San Diego Moores Cancer Center
RECRUITING

La Jolla, California, 92037, United States

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UCLA Department of Medicine - Hematology/Oncology
RECRUITING

Los Angeles, California, 90095, United States

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UCSF Helen Diller Family Comprehensive Cancer Center
RECRUITING

San Francisco, California, 94143, United States

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UPMC
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States

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USC Norris Comprehensive Cancer Center
RECRUITING

Los Angeles, California, 90033, United States

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Universitatsklinikum Mainz Hautklinik und Poliklinik
RECRUITING

Mainz, 55131, Germany

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University of Colorado Hospital - Anschutz Cancer Pavilion
RECRUITING

Aurora, Colorado, 80045, United States

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University of Iowa
RECRUITING

Iowa City, Iowa, 52242, United States

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University of Kansas Cancer Center
RECRUITING

Westwood, Kansas, 66205, United States

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University of Kiel
RECRUITING

Kiel, 24105, Germany

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University of Louisville Brown Cancer Center
RECRUITING

Louisville, Kentucky, 40202, United States

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University of Minnesota
RECRUITING

Minneapolis, Minnesota, 55455, United States

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University of North Carolina at Chapel Hill
RECRUITING

Chapel Hill, North Carolina, 27514, United States

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University of Tennessee
RECRUITING

Knoxville, Tennessee, 37920, United States

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University of Texas Southwestern Medical Center
RECRUITING

Dallas, Texas, 75390, United States

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University of Vermont Medical Center
RECRUITING

Burlington, Vermont, 05401, United States

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Universitätsklinikum Essen
RECRUITING

Essen, 45147, Germany

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Universitätsklinikum Hospital Heidelberg
RECRUITING

Heidelberg, 69120, Germany

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Universitätsklinikum Medical Center
RECRUITING

Hamburg, 20246, Germany

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Universitätsklinikum of Tübingen
RECRUITING

Tübingen, 72076, Germany

Contact
Uniwersyteckie Centrum Kliniczne
RECRUITING

Gdansk, 80-214, Poland

Contact
West Cancer Center and Research Institute
RECRUITING

Germantown, Tennessee, 38138, United States

Contact
West Virginia University
RECRUITING

Morgantown, West Virginia, 26506, United States

Contact
Winship Cancer Institute, Emory University
RECRUITING

Atlanta, Georgia, 30322, United States

Contact

Conditions

Explore the condition pages connected to this study.

ADVANCED MELANOMA