New Two-Pronged attack on deadly melanoma in the brain
NCT ID NCT06887088
Summary
This trial is testing a new treatment strategy for people with a specific type of advanced skin cancer (BRAF-mutated melanoma) that has spread to the brain and is causing symptoms. It will give 33 participants two targeted drugs (encorafenib and binimetinib) for about two months, followed by two immunotherapy drugs (cemiplimab and fianlimab) for up to two years. The main goal is to see if this sequence can keep the brain tumors from growing for at least six months in more patients than previous treatments.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Locations
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Clinico Universitario Virgen de la Arrixaca
RECRUITINGMurcia, Murcia, 30120, Spain
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Complejo Hospitalario Universitario A Coruña
RECRUITINGA Coruña, A Coruña, 15006, Spain
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Hospital Clinico San Carlos
RECRUITINGMadrid, Madrid, 28040, Spain
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Hospital Clínic de Barcelona
RECRUITINGBarcelona, Barcelona, 08036, Spain
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Hospital Clínico Universitario Valencia.
RECRUITINGValencia, Valencia, 46010, Spain
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Hospital General Universitario de Valencia
RECRUITINGValencia, Valencia, 46014, Spain
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Hospital Regional Universitario de Málaga
RECRUITINGMálaga, Málaga, 29010, Spain
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Hospital Universitario Gregorio Marañon
NOT_YET_RECRUITINGMadrid, Madrid, 28007, Spain
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Hospital Universitario Marqués de Valdecilla
RECRUITINGSantander, Cantabria, 39008, Spain
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Hospital Universitario Puerta del Hierro
RECRUITINGMajadahonda, Madrid, 28222, Spain
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Hospital Universitario Ramón y Cajal
RECRUITINGMadrid, Madrid, 28034, Spain
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Hospital Universitario San Pedro de Alcántara
RECRUITINGCáceres, Cáceres, 10003, Spain
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Hospital Universitario Vall d´Hebron
RECRUITINGBarcelona, Barcelona, 08035, Spain
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Hospital Universitario de Burgos
RECRUITINGBurgos, Burgos, 09006, Spain
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Hospital Virgen de la Macarena (Sevilla)
RECRUITINGSeville, Sevilla, 41009, Spain
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Instituto Catalán de Oncología - Hospital Duran i Reynals
RECRUITINGBarcelona, Barcelona, 08908, Spain
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Onkologikoa (Donostia)
RECRUITINGDonostia / San Sebastian, Donostia, 20014, Spain
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Quiron Dexeus - IOR
RECRUITINGBarcelona, Barcelona, 08028, Spain
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Conditions
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