Experimental MegaLT injection targets dangerous low platelets in early trial

NCT ID NCT06534255

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tests a new cell therapy called MegaLT for people with dangerously low platelet counts that don't improve after radiation, chemotherapy, or stem cell transplant. Only 10 participants will receive the injection at different doses to check safety and how the body handles it. The study is not yet recruiting and focuses on finding a safe dose, not proving it works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MegaLT injection (a cell therapy)

What this could lead to

If it works, this could point toward a new treatment for dangerously low platelet counts that don't respond to standard care.

What could go wrong

This is a very early, tiny Phase 1 trial with only 10 people. It primarily checks safety, not effectiveness. The treatment may not work or could cause side effects like graft-versus-host disease.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

thrombocytopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital)

    Hefei, Anhui, 230036, China