New drug combo shows promise against tough cancers

NCT ID NCT03530397

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tests a new drug called MEDI5752, given alone or with chemotherapy, in adults with advanced solid tumors that have not responded to other treatments. The main goals are to check safety, find the right dose, and see if the drug can shrink tumors. About 400 participants will take part to help researchers understand how well the drug works and what side effects may occur.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Site

    Detroit, Michigan, 48202, United States

  • Research Site

    New York, New York, 10065, United States

  • Research Site

    Chapel Hill, North Carolina, 27599, United States

  • Research Site

    Providence, Rhode Island, 02903, United States

  • Research Site

    Chattanooga, Tennessee, 37404, United States

  • Research Site

    Nashville, Tennessee, 37203, United States

  • Research Site

    Fairfax, Virginia, 22031, United States

  • Research Site

    Melbourne, 3000, Australia

  • Research Site

    Melbourne, 3004, Australia

  • Research Site

    Randwick, 2031, Australia

  • Research Site

    Bordeaux, 33075, France

  • Research Site

    Lyon, 69373, France

  • Research Site

    Villejuif, 94805, France

  • Research Site

    Meldola, 47014, Italy

  • Research Site

    Naples, 80131, Italy

  • Research Site

    Ravenna, 48121, Italy

  • Research Site

    Roma, 168, Italy

  • Research Site

    Amsterdam, 1066 CX, Netherlands

  • Research Site

    Lisbon, 1649-035, Portugal

  • Research Site

    Porto, 4200-072, Portugal

  • Research Site

    Cheongju-si, 28644, South Korea

  • Research Site

    Gyeonggi-do, 13620, South Korea

  • Research Site

    Incheon, 21565, South Korea

  • Research Site

    Seoul, 03080, South Korea

  • Research Site

    Seoul, 03722, South Korea

  • Research Site

    Seoul, 05505, South Korea

  • Research Site

    Seoul, 06351, South Korea

  • Research Site

    A Coruña, 15006, Spain

  • Research Site

    Barcelona, 08003, Spain

  • Research Site

    Barcelona, 08028, Spain

  • Research Site

    Barcelona, 08035, Spain

  • Research Site

    Barcelona, 08041, Spain

  • Research Site

    Barcelona, 08916, Spain

  • Research Site

    Majadahonda, 28222, Spain

  • Research Site

    Málaga, 29010, Spain

  • Research Site

    Pamplona, 31008, Spain

  • Research Site

    Valencia, 46010, Spain

  • Research Site

    Taichung, 40705, Taiwan

  • Research Site

    Tainan, 70403, Taiwan

  • Research Site

    Taipei, 10048, Taiwan