New hope for kids with Hard-to-Treat TB: bedaquiline combo under study

NCT ID NCT02354014

First seen Sep 30, 2025 · Last updated May 08, 2026 · Updated 26 times

Summary

This study is testing a drug called bedaquiline (TMC207) in children and teens (0 to 18 years old) who have multidrug-resistant tuberculosis (MDR-TB). The goal is to see how safe the drug is, how the body processes it, and how well it works when given with other TB medicines. About 60 participants will take the drug combination and be monitored for side effects and treatment success.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • De La Salle Health Sciences Institute- DLSUMC

    RECRUITING

    Dasmariñas, 4114, Philippines

  • Desmond Tutu TB Centre

    RECRUITING

    Stellenboch, 7600, South Africa

  • First Moscow State Medical University n.a. I.M. Sechenov

    COMPLETED

    Moscow, 119991, Russia

  • Hospital Geral da Polana Caniço

    RECRUITING

    Maputo, 00000, Mozambique

  • Lung Center Of The Philippines

    COMPLETED

    Quezon City, 1100, Philippines

  • Makerere University Lung Institute

    TERMINATED

    Kampala, Uganda

  • Silang Specialists Medical Center

    RECRUITING

    San Vincent Silang, 000, Philippines

  • Sizwe Tropical Diseases Hospital

    RECRUITING

    Johannesburg, 2131, South Africa

  • State Institute Of Phthisiology And Pulmonology N.A. F.G. Yanovskiy Of Ams Ukraine

    COMPLETED

    Kiev, 3038, Ukraine

  • THINK: Tuberculosis & HIV Investigative Network

    COMPLETED

    Durban, 4001, South Africa

  • Wits Health Consortium

    RECRUITING

    Port Elizabeth, 6200, South Africa

Conditions

Explore the condition pages connected to this study.