New liver safety study for experimental drug MDR-001 begins

NCT ID NCT07550634

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage study will give a single dose of MDR-001, a GLP-1 receptor agonist tablet, to 32 people: some with mild or moderate liver impairment and some with healthy livers. Researchers want to see how the drug moves through the body and if it is safe in people with liver issues. The goal is to gather information, not to treat the liver condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MDR-001 (a GLP-1 receptor agonist tablet)

What this could lead to

If successful, this study could help doctors understand how to safely dose MDR-001 in patients with liver problems.

What could go wrong

This is a very early Phase 1 trial with only 32 participants. It is designed to measure drug levels and safety, not to treat liver disease. Results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

follicular lymphoma Hepatic Insufficiency liver disorder liver failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Hospital of Jilin University

    Changchun, Jilin, 130021, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••