New psoriasis cream shows promise in major trial

NCT ID NCT07357831

Ongoing Disease control Sponsor: Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This phase 3 trial tests a new cream (MC2-01) containing two active ingredients for plaque psoriasis in Chinese adults. About 537 participants will use either the new cream, a standard gel, or a placebo cream for 8 weeks. The main goal is to see if the new cream clears skin better than the alternatives.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MC2-01 cream (calcipotriene and betamethasone dipropionate combination)

What this could lead to

If successful, this cream could offer a more effective or convenient topical treatment option for plaque psoriasis, potentially improving skin clearing.

What could go wrong

This is a late-stage trial, but results may not apply to all populations. The cream might not be significantly better than existing gels, and side effects like skin irritation are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

psoriasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PLAQUE PSORIASIS

Contacts and locations

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Locations

Affiliated Hospital of Jiangsu University

Zhenjiang, Jiangsu, China
Beijing Aerospace General Hospital

Beijing, Beijing Municipality, China
Bejjing Friendship Hospital，Capital Medical University

Beijing, Beijing Municipality, China
Chengde Medical University Affiliated Hospital

Chengde, Hebei, China
Chengdu Second People 's Hospital

Chengdu, Sichuan, China
Chongqing Hospital of Traditional Chinese Medicine

Chongqing, Chongqing Municipality, China
First Hospital of Hebei Medical University

Shijiazhuang, Hebei, China
Fujian Medical University Union Hospital

Fuzhou, Fujian, China
Guangzhou First People's Hospital

Guangzhou, Guangdong, China
Haikou Fifth People's Hospital

Haikou, Hainan, China
Hangzhou First People's Hospital

Hangzhou, Zhejiang, China
Henan University of Science and Technology Second Affiliated Hospital

Luoyang, Henan, China
Huashan Hospital, Fudan University

Shanghai, Shanghai Municipality, China
Hunan University of Medicine General Hospital

Huaihua, Hunan, China
Inner Mongolia Baogang Hospital

Baotou, Inner Mongolia, China
Jinan Central Hospital

Jinan, Shandong, China
Jingzhou Central Hospital

Jingzhou, Hubei, China
Jining NO.1 People's Hospital

Jining, Shandong, China
Nanyang Central Hospital

Nanyang, Henan, China
Sanmenxia Central Hospital

Sanmenxia, Henan, China
Shanghai Skin Disease Hospital

Shanghai, Shanghai Municipality, China
Shenyang Medical College Affiliated Central Hospital

Shenyang, Liaoning, China
Shenzhen Nanshan District People's Hospital

Shenzhen, Guangdong, China
Shenzhen Second People's Hospital

Shenzhen, Guangdong, China
Shiyan Renmin Hospital

Shiyan, Hubei, China
Sir Run Run Shaw Hospital, affiliated with the Zhejiang University School of Medicine

Hangzhou, Zhejiang, China
Southern Medical University Dermatology Hospital

Guangzhou, Guangdong, China
Suining Central Hospital

Suining, Sichuan, China
Sun Yat-sen Memorial Hospital, Sun Yat-sen University

Guangzhou, Guangdong, China
Sun Yat-sen University Third Affiliated Hospital

Guangzhou, Guangdong, China
Suzhou Municipal Hospital

Suzhou, Jiangsu, China
Taihe Hospital

Shiyan, Hubei, China
Taiyuan Central Hospital

Taiyuan, Shanxi, China
The Affiliated Hospital Of Xuzhou Medical University

Xuzhou, Jiangsu, China
The First Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, China
The First Affiliated Hospital of Fujian Medical University

Fuzhou, Fujian, China
The First Affiliated Hospital of Gannan Medical University

Ganzhou, Jiangxi, China
The First Affiliated Hospital of Guilin Medical University

Guilin, Guangxi, China
The First Affiliated Hospital of NingBo University

Ningbo, Zhejiang, China
The First Hospital of Jiaxing

Jiaxing, Zhejiang, China
The First Hospital of Jilin University

Changchun, Jilin, China
The First People's Hospital of Lianyungang

Lianyungang, Jiangsu, China
The Second Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, China
The Second Affiliated Hospital of Harbin Medical University

Harbin, Heilongjiang, China
The Second Affiliated Hospital of Wannan Medical College

Wuhu, Anhui, China
The Second Affiliated Hospital of Xiamen medical college

Xiamen, Fujian, China
The Second Xiangya Hospital of Central South University

Changsha, Hunan, China
The Third Xiangya Hospital of Central South University

Changsha, Hunan, China
Wuxi People's Hospital

Wuxi, Jiangsu, China
Wuxi Second People's Hospital

Wuxi, Jiangsu, China
Xiangya Hospital of Central South University

Changsha, Hunan, China
Yancheng NO.1 People's Hospital

Yancheng, Jiangsu, China
Zhejiang Provincial People's Hospital

Hangzhou, Zhejiang, China
Zhengzhou Central Hospital

Zhengzhou, Henan, China
Zhujiang Hospital of Southern Medical University

Guangzhou, Guangdong, China