New hope for Tough-to-Treat T-Cell lymphoma: experimental therapy MB-105 enters phase 2

NCT ID NCT06534060

First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 22 times

Summary

This study tests an experimental drug called MB-105 in about 46 adults with a specific type of T-cell lymphoma (CD5-positive) that has returned or not responded to standard treatments. The goal is to see if the drug can shrink or control the cancer and to check for side effects. Participants will receive MB-105 and be monitored for tumor response and safety.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Baylor College of Medicine

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

  • Cleveland Clinic

    NOT_YET_RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Email: •••••@•••••

    Contact

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact

  • Moffitt Cancer Center Magnolia Campus

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Oregan Health & Science University

    NOT_YET_RECRUITING

    Portland, Oregon, 97239, United States

    Contact

  • SCRI - Colorado Blood Cancer Institute (CBCI)

    NOT_YET_RECRUITING

    Denver, Colorado, 92037, United States

  • University of Iowa

    RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Nebraska

    RECRUITING

    Omaha, Nebraska, 68198, United States

    Contact

  • University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

    Contact Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of San Diego (UCSD)-Moores Cancer Center

    RECRUITING

    San Diego, California, 92037, United States

    Contact Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.