New heart drug shows promise for treating thickened heart muscle condition

NCT ID NCT05414175

Summary

This study tested whether a 30-week course of the drug mavacamten is effective and safe for Japanese adults with symptomatic obstructive hypertrophic cardiomyopathy (HCM), a condition where the heart muscle thickens and obstructs blood flow. The trial involved 38 participants and measured changes in heart function, symptoms, and quality of life. Researchers wanted to see if the drug could reduce the heart's obstruction and improve how patients feel during daily activities.

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Contacts and locations

Locations

  • Local Institution - 0001

    Itabashi-Ku, Tokyo, 173-0003, Japan

  • Local Institution - 0003

    Fuchu-Shi, Tokyo, 1830003, Japan

  • Local Institution - 0005

    Shinjuku-Ku, Tokyo, 160-8582, Japan

  • Local Institution - 0007

    Koto-Ku, Tokyo, 135-0061, Japan

  • Local Institution - 0009

    Chuo-Ku, Tokyo, 104-0044, Japan

  • Local Institution - 0010

    Bunkyo-Ku, Tokyo, 113-0033, Japan

  • Local Institution - 0011

    Suita-Shi, Osaka, 565-0871, Japan

  • Local Institution - 0012

    Hamamatsu, Shizuoka, 431-3192, Japan

  • Local Institution - 0013

    Shinjuku-ku, Tokyo, 162-8666, Japan

  • Local Institution - 0014

    Suita, Osaka, 564-8565, Japan

  • Local Institution - 0015

    Nankoku-shi, Kochi, 783-8505, Japan

  • Local Institution - 0016

    Kobe, Hyōgo, 650-0047, Japan

  • Local Institution - 0017

    Tsukuba, Ibaraki, 305-0005, Japan

  • Local Institution - 0018

    Osaka, 558-8558, Japan

  • Local Institution - 0019

    Yokohama, Kanagawa, 227-8501, Japan

  • Local Institution - 0020

    Uwajima, Ehime, 798-8510, Japan

  • Local Institution - 0023

    Kanazawa, Ishikawa-ken, 920-8641, Japan

  • Local Institution - 0026

    Himeji-Shi, Hyōgo, 672-8044, Japan

  • Local Institution - 0027

    Sendai, Miyagi, 980-8574, Japan

  • Local Institution - 0028

    Tsu, Mie-ken, 514-8507, Japan

Conditions

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