Scientists track mystery Drug's journey through healthy volunteers
NCT ID NCT07644442
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed Phase 1 study gave 6 healthy Chinese men a single oral dose of a radiolabeled drug called HMPL-453 to see how it is absorbed, broken down, and eliminated. Researchers measured radioactivity in blood, urine, and feces over time. The goal was not to treat any disease but to understand the drug's path in the body, which is essential for planning future studies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
HMPL-453 (a drug being studied, given as a single oral dose with a radioactive tracer)
What this could lead to
If successful, this study will show how HMPL-453 moves through and leaves the body, helping design future trials for diseases it may treat.
What could go wrong
This is a very early, small study in just 6 healthy men, not patients. It only tracks the drug's path in the body and does not test if it works for any disease.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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The First Affiliated Hospital of Shandong First Medical University (Shandong Provincial Qianfoshan Hospital)
Jinan, Shandong, 250000, China