New marburg vaccine shows promise in early human trial

NCT ID NCT06265012

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-stage trial tested a new vaccine called PHV01 against Marburg virus, a rare but severe disease. 36 healthy adults received either the vaccine or a placebo to check safety and immune response. The study aims to find a safe dose and see if the vaccine triggers antibodies against the virus.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Marburg virus vaccine (PHV01)
What this could lead to
If successful, this could lead to a safe and effective vaccine to prevent Marburg virus disease, a rare but often fatal illness.
What could go wrong
This is an early Phase 1 trial with only 36 people, so results may not apply to larger populations. The vaccine may not produce a strong enough immune response or could have unexpected side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CenExel RCA

    Hollywood, Florida, 33024, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.