New hope for debilitating itch in liver disease patients
NCT ID NCT06553768
Summary
This study is testing whether the drug maralixibat is safe and effective at reducing severe, treatment-resistant itching in children and adults with cholestatic liver disease. Participants will be randomly assigned to receive either the study drug or a placebo (inactive substance) for comparison. The main goal is to see if maralixibat can significantly lower the severity of the itching, which has no other treatment options for these patients.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Azienda Ospedaliera Papa Giovanni XXIII
RECRUITINGBergamo, 24127, Italy
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Baylor College of Medicine
RECRUITINGHouston, Texas, 77030, United States
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Children's Hospital Los Angeles (CHLA)
RECRUITINGLos Angeles, California, 90027, United States
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Children's Hospital of Philadelphia
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Cincinnati Children's Hospital Medical Center
RECRUITINGCincinnati, Ohio, 45229, United States
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Consultario de Joshue David Covarrubias Esquer
NOT_YET_RECRUITINGZapopan, Mexico
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Hospital Infantil de México Federico Gómez
NOT_YET_RECRUITINGMexico City, Mexico
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Hospital Sant Joan de Deu
RECRUITINGBarcelona, Spain
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Hospital Sírio-Libanês
RECRUITINGSão Paulo, Brazil
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Hospital Universitario La Paz
RECRUITINGMadrid, Spain
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Hospital Universitario Vall d'Hebron
RECRUITINGBarcelona, Spain
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Hospital da Criança Santo Antonio
RECRUITINGPorto Alegre, Brazil
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Hospital de Criança de Brasília (HCB)
RECRUITINGBrasília, Brazil
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Hotel Dieu de France
RECRUITINGBeirut, Lebanon
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Hôpital Femme Mère Enfant
RECRUITINGLyon, France
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Hôpital Kremlin Bicêtre
RECRUITINGParis, France
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Hôpitaux Universitaires de Marseille Timone
RECRUITINGMarseille, 13005, France
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ISMETT - Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione
RECRUITINGPalermo, 90127, Italy
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Instytut Pomnik Centrum Zdrowia Dziecka
RECRUITINGWarsaw, Poland
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King Faisal Specialist Hospital & Research Center
RECRUITINGRiyadh, 12713, Saudi Arabia
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King's College Hospital NHS Foundation Trust
RECRUITINGLondon, United Kingdom
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LMU Klinikum - Kinderklinik und Kinderpoliklinik im Dr. von Haunerschen Kinderspital
RECRUITINGMunich, Germany
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Lurie Children's Hospital
RECRUITINGChicago, Illinois, 60611, United States
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Morgan Stanley Children's Hospital - NewYork Presbyterian
RECRUITINGNew York, New York, 10032, United States
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Mount Sinai Hospital
RECRUITINGNew York, New York, 10029, United States
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NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
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Ochsner Clinic Foundation
RECRUITINGNew Orleans, Louisiana, 70121, United States
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Ospedale Pediatrico Bambino Gesu
RECRUITINGRome, 00165, Italy
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Science 37, Inc (Remote-homebase Telemedicine)
RECRUITINGMorrisville, North Carolina, 27520, United States
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Seattle Children's Hospital
RECRUITINGSeattle, Washington, 98105, United States
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Stanford Children's Health in Palo Alto
RECRUITINGPalo Alto, California, 94304, United States
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Stollery Children's Hospital
RECRUITINGEdmonton, Alberta, T6G 2B7, Canada
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University of Utah
RECRUITINGSalt Lake City, Utah, 84112, United States
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Universitätsklinikum Hamburg Eppendorf - Klinik für Kinder- und Jugendmedizin
RECRUITINGHamburg, Germany
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Vanderbilt University Medical Center
RECRUITINGNashville, Tennessee, 37232, United States
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Conditions
Explore the condition pages connected to this study.