New drug combo trial aims to wipe out hidden cancer cells
NCT ID NCT04802590
Summary
This trial is testing two different drug combinations for people newly diagnosed with mantle cell lymphoma, a type of blood cancer. It will compare a two-drug regimen (ibrutinib plus an antibody) against a three-drug regimen that adds a medication called venetoclax. The main goal is to see which combination is better at reducing hidden cancer cells in the blood and bone marrow after six months of treatment.
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Contacts and locations
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Locations
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A.Z. Sint Jan AV
Bruges, 8000, Belgium
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CH Henri Mondor
Créteil, 94010, France
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CH d'Avignon - Hopital Henri Duffaut
Avignon, 84000, France
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CH de Bretagne Atlantique - Hopital CHUBERT
Vannes, 56017, France
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CH de Cornouaille
Quimper, 29107, France
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CH de la Côte Basque
Bayonne, 64109, France
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CHD de Vendée
La Roche-sur-Yon, 85925, France
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CHRU de Lille
Lille, 59037, France
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CHU Bretonneau
Tours, 37044, France
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CHU Jean Minioz
Besançon, 25030, France
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CHU Nancy Brabois
Vandœuvre-lès-Nancy, 54511, France
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CHU Pontchaillou
Rennes, 35033, France
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CHU d'Angers
Angers, 49033, France
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CHU de DIJON
Dijon, 21000, France
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CHU de Grenoble
La Tronche, 38700, France
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CHU de Liege
Liège, 4000, Belgium
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CHU de Montpellier
Montpellier, 34295, France
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CHU de Nantes
Nantes, 44093, France
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CHU de REIMS
Reims, 51092, France
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Centre Henri BECQUEREL
Rouen, 76038, France
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Centre Hospitalier Lyon Sud
Pierre-Bénite, 69495, France
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Centre Léon Bérard
Lyon, 69373, France
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Ch Annecy Gennevois
Pringy, 74374, France
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Chu Estaing
Clermont-Ferrand, 63003, France
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Chu de Bordeaux - Hopital Haut-Leveque - Centre Francois Magendie
Pessac, 33604, France
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Chu de Brest - Hopital de La Cavale Blanche
Brest, 29609, France
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Hopital DUPUYTREN
Limoges, 87042, France
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Hopital Jolimont
Haine-Saint-Paul, 7100, Belgium
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Hopital NECKER
Paris, 75743, France
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Hopital René Huguenin
Saint-Cloud, 92210, France
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Hopital St-Louis
Paris, 75475, France
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Hopital de la Milétrie
Poitiers, 86021, France
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IUCT Oncopole
Toulouse, 31100, France
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Institut Gustave ROUSSY
Villejuif, 94805, France
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Institut Paoli Calmettes
Marseille, 13273, France
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Institut d'Hématologie de Basse Normandie
Caen, 14033, France
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Institut de Cancérologie Strasbourg Europe
Strasbourg, 67033, France
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Institut de Cancérologie de la Loire Lucien Neuwirth
Saint-Priest-en-Jarez, 42270, France
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Norfolk and Norwich University Hospitals NHS Foundation Trust
Norwich, NR4 7UY, United Kingdom
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Oxford University Hospitals NHS Foundation Trust
Oxford, OX3 7LE, United Kingdom
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Royal Cornwall Hospital Trust
Truro, TR1 3LJ, United Kingdom
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The Christie NHS Foundation Trust
Manchester, M20 4BX, United Kingdom
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Universite Catholique de Louvain Mont Godinne
Yvoir, 5530, Belgium
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Universite Libre de Bruxelles - Hopital ERASME
Brussels, 1070, Belgium
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University Hospitals Plymouth NHS Trust
Plymouth, PL6 8DH, United Kingdom
Conditions
Explore the condition pages connected to this study.