New drug combo aims to control rare blood cancer in older adults

NCT ID NCT07206264

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 22 times

Summary

This study tests a combination of chemotherapy (bendamustine) and targeted therapy (orelabrutinib plus an anti-CD20 antibody) as a first treatment for mantle cell lymphoma. It includes 45 adults aged 60 or older who cannot or choose not to have a stem cell transplant. The goal is to see if this approach improves how long the cancer stays under control, using PET scans and MRD tests to guide treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MANTLE CELL LYMPHOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fujian Provincial Cancer Hospital

    Fuzhou, Fujian, China

  • Harbin Medical University Cancer Hospital

    Harbin, Heilongjiang, China

  • Hebei Medical University Tumor Hospital

    Shijiazhuang, Hebei, China

  • Shandong Cancer Hospital

    Jinan, Shandong, China

  • Tianjin Medical University Cancer Institute and Hospital

    Tianjin, China

Conditions

Explore the condition pages connected to this study.