New hope for mantle cell lymphoma: combo therapy aims to improve remission
NCT ID NCT06854003
First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 30 times
Summary
This study tests a new combination of drugs (bendamustine, rituximab, cytarabine, and zanubrutinib) as initial treatment for mantle cell lymphoma, followed by a maintenance phase with or without an additional drug (sonrotoclax). The goal is to see if this approach leads to a complete response with no detectable cancer cells after one year. The study involves 60 adults who have not received prior lymphoma therapy.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Brigham and Women's Hospital
ACTIVE_NOT_RECRUITINGBoston, Massachusetts, 02215, United States
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
Contact
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mayo Clinic
NOT_YET_RECRUITINGRochester, Minnesota, 55905, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mayo Clinic Arizona
NOT_YET_RECRUITINGPhoenix, Arizona, 85054, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Washington University
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.