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Scientists dig into why mantle cell lymphoma beats First-Line therapy

NCT ID NCT04882475

Ongoing Knowledge-focused Sponsor: Fondazione Italiana Linfomi - ETS Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study examines stored tissue samples from 160 adults with mantle cell lymphoma whose cancer returned or didn't respond after initial chemotherapy and rituximab. Researchers will analyze the samples to identify genetic and cellular features linked to treatment resistance. The goal is to gather knowledge that could guide future therapies, but no new treatments are given to participants.

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Conditions

The condition(s) this trial relates to.

mantle cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MANTLE CELL LYMPHOMA

Contacts and locations

Locations

  • A.O. S. Croce e Carle

    Cuneo, 12100, Italy

  • A.O.U. Citta della Salute e della Scienza di Torino- Ematologia Universitaria

    Torino, Italy

  • AOU Integrata di Verona - U.O. Ematologia

    Verona, 37134, Italy

  • AOU Maggiore della Carità di Novara - SCDU Ematologia

    Novara, 28100, Italy

  • AOU Senese - U.O.C. Ematologia

    Siena, SI, 53100, Italy

  • AOU di Padova - Ematologia

    Padova, 35121, Italy

  • ASST Grande Ospedale Metropolitano Niguarda

    Milan, MI, 20162, Italy

  • ASST Spedali Civili di Brescia - Ematologia

    Brescia, Italy

  • Azienda Ospedaliera Universitaria Careggi- Unità funzionale di ematologia

    Florence, 50134, Italy

  • Azienda Sanitaria Universitaria Friuli Centrale (ASU FC) - SOC Clinica Ematologica

    Udine, Italy

  • Azienda Sanitaria Universitaria Giuliano Isontina (ASUGI) - SC Ematologia

    Trieste, Italy

  • Azienda Unitа Sanitaria Locale-IRCCS - Arcispedale Santa Maria Nuova - Ematologia - Ematologia

    Reggio Emilia, Italy

  • Centro Riferimento Oncologico - S.O.C. Oncologia Medica A

    Aviano, Italy

  • Ospedale Ca' Foncello - S.C di Ematologia

    Treviso, Italy

  • Ospedale Guglielmo da Saliceto - U.O.Ematologia

    Piacenza, 29121, Italy

  • ULSS 8 Berica - Ospedale S. Bortolo - Ematologia

    Vicenza, Italy

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