One-Dose malaria shield? new combo aims to clear and protect
NCT ID NCT05974267
First seen Nov 01, 2025 · Last updated May 02, 2026 · Updated 26 times
Summary
This study tested whether a single dose of two drugs (M5717 and pyronaridine) can clear hidden malaria parasites from the blood and prevent new infections. It involved 192 asymptomatic adults and teens with malaria. The goal was to see how long protection lasts and if the combination is safe.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Groupe de Recherche Action en Sante (GRAS)
Ouagadougou, Burkina Faso
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Kisumu County Referral Hospital
Kisumu, Kenya
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MRC Unit The Gambia at LSHTM
Banjul, The Gambia
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Ndola Teaching Hospital
Ndola, Zambia
Conditions
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