Shock therapy maintenance may keep schizophrenia at bay

NCT ID NCT06456983

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether maintenance electroconvulsive therapy (ECT) can prevent relapse in people with schizophrenia that doesn't respond to the strongest medications. About 140 participants who improved after a course of ECT will either continue with maintenance ECT or receive usual care. The goal is to see if maintenance ECT delays or reduces the chance of relapse.

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Conditions

The condition(s) this trial relates to.

schizophrenia Schizophrenia, Treatment-Resistant treatment-refractory schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Clinic for Psychiatry, Saarbrücken

    NOT_YET_RECRUITING

    Saarbrücken, Germany

  • Department of Psychiatry and Psychotherapy, Central Institute of Mental Health (CIMH)

    RECRUITING

    Mannheim, 68159, Germany

  • Departmet of Psychiatry, University Medical Center Göttingen

    NOT_YET_RECRUITING

    Göttingen, Germany

  • Dept. of Psychiatry I, Wiesloch

    NOT_YET_RECRUITING

    Wiesloch, Germany

  • Dept. of Psychiatry, Hannover Medical School

    NOT_YET_RECRUITING

    Hanover, Germany

  • Dept. of Psychiatry, LMU München

    NOT_YET_RECRUITING

    München, Germany

  • Dept. of Psychiatry, RWTU Aachen

    NOT_YET_RECRUITING

    Aachen, Germany

  • Dept. of Psychiatry, University Mainz

    NOT_YET_RECRUITING

    Mainz, Germany

  • Dept. of Psychiatry, University Tübingen

    NOT_YET_RECRUITING

    Tübingen, Germany

  • Dept. of Psychiatry, University of Augsburg

    NOT_YET_RECRUITING

    Augsburg, Germany

  • Klinik für Psychiatrie, Göppingen

    NOT_YET_RECRUITING

    Göppingen, Germany

  • Klinik für Psychiatrie, Siegen

    NOT_YET_RECRUITING

    Siegen, Germany

  • Universitätsklinikum Heidelberg, Klinik für Allgemeine Psychiatrie

    NOT_YET_RECRUITING

    Heidelberg, 69115, Germany

  • Zentrum für Psychische Gesundheit

    NOT_YET_RECRUITING

    Ingolstadt, Germany

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