Drug combo tested in fight against tough head and neck cancers

NCT ID NCT04854499

Terminated Disease control Sponsor: Gilead Sciences Source: ClinicalTrials.gov ↗

Summary

This study tested whether adding an experimental drug called magrolimab to other cancer therapies could help control advanced head and neck cancer. It involved 193 people whose cancer had spread or returned and could not be cured with surgery or radiation. The main goals were to check the safety of these drug combinations and see if they could slow cancer growth or shrink tumors.

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Contacts and locations

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Locations

ASST degli Spedali Civili di Brescia

Brescia, 25123, Italy
AZ Sint-Maarten

Mechelen, 2800, Belgium
Alfred Health

Melbourne, Victoria, 3004, Australia
Algemeen Ziekenhuis Klina

Brasschaat, 2930, Belgium
Arcispedale Santa Maria Nuova

Reggio Emilia, 42100, Italy
Astera Cancer Care

East Brunswick, New Jersey, 08816, United States
Austin Health

Heidelberg, Victoria, 3084, Australia
Avera Cancer Institute

Sioux Falls, South Dakota, 57105, United States
Azienda Ospedaliero - Universitaria Senese

Siena, 53100, Italy
Azienda Ospedaliero - Universitaria di Bologna - IRCCS

Bologna, 40138, Italy
Azienda Ospedaliero-Universitaria di Modena - Policlinico

Modena, 41124, Italy
Blacktown Hospital

Westmead, New South Wales, 2145, Australia
CHU UCL Namur - Sainte-Elisabeth

Namur, 5000, Belgium
Cairns Hospital

Cairns, Queensland, 4870, Australia
Centre Georges François Leclerc

Dijon, 21079, France
Centre Hospitalizer De L'Ardenne

Libramont-Chevigny, 6800, Belgium
Centre Léon Bérard

Lyon, 69373, France
Centre de Lutte Contre le Cancer (CLCC) - Centre Antoine Lacassagne (CAL) - Site Est

Nice, 6189, France
Centro Hospitalar Universitario do Porto

Porto, 4050-011, Portugal
Centro Hospitalar do Algarve

Faro, 8000-366, Portugal
Centrum Onkologii im. Prof. Franciszka Lukaszczyka w Bydgoszczy

Bydgoszcz, 85-796, Poland
Charite University Medicine

Berlin, 10177, Germany
City of Hope

Duarte, California, 91010, United States
Civils de Lyon-Centre Hopitalier Lyon Sud

Pierre-Bénite, 69310, France
Clinica Universidad de Navarra

Pamplona, 31008, Spain
Fondazione IRCCS Istituto Nazionale Tumori Milano

Milan, 20133, Italy
Hopital Foch

Suresnes, 92151, France
Hopital Pitie-Salpetriere

Paris, 75013, France
Hopital de la Timone

Marseille, 13005, France
Hospital CUF Descobertas

Lisbon, 1998-018, Portugal
Hospital Clínico Universitario de Valencia

Valencia, Spain
Hospital De La Santa Creu I Sant Pau

Barcelona, 8041, Spain
Hospital General Universitario Gregorio Maranon

Madrid, 28007, Spain
Hospital Regional Universitario de Malaga

Málaga, 29010, Spain
Hospital Universitari Vall d'Hebron

Barcelona, 08035, Spain
Hospital Universitari i Politecnic La Fe

Valencia, 46026, Spain
Hospital Universitario La Paz

Madrid, 28046, Spain
Hospital Universitario Virgen Macarena

Seville, 41009, Spain
Hospital Universitario Virgen del Rocio

Seville, 41013, Spain
Hospital Universitario de Jaen

Jaén, 23007, Spain
Hospital de Braga

Braga, 4710-243, Portugal
Hospital del Mar

Barcelona, 8003, Spain
Huntsman Cancer Institute

Salt Lake City, Utah, 84112, United States
Icahn School of Medicine at Mount Sinai and the Mount Sinai Hospital

New York, New York, 10029, United States
Indiana University Melvin and Bren Simon Cancer Center

Indianapolis, Indiana, 46202, United States
Institut Bergonie

Bordeaux, 33000, France
Institut Curie

Paris, 75005, France
Institut Gustave Roussy

Villejuif, 94805, France
Instituto Portugues de Oncologia Do Porto Francisco Gentil,E.P.E.

Porto, 4200-072, Portugal
Ironwood Cancer and Research Center

Chandler, Arizona, 85224, United States
Kath. Marienkrankenhaus gGmbH

Hamburg, 22087, Germany
Lancaster General Hospital

Lancaster, Pennsylvania, 17602, United States
MD Anderson Cancer Center

Houston, Texas, 77030, United States
MD Anderson Cancer Center

Madrid, 28033, Spain
Macquarie University

Macquarie Park, New South Wales, 2109, Australia
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Memorial Healthcare System

Hollywood, Florida, 33021, United States
Musgrove Park Hospital

Taunton, TA1 5DA, United Kingdom
Narodowy Instytut Onkologii im. M. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy, Klinika Nowotworow Glowy i Szyi

Warsaw, 2781, Poland
Narodowy Instytut Onkologii im. M. Sklodowskiej-Curie, Panstwowy Instytut Badawczy, Oddzial x Gliwicach

Gliwice, 44-102, Poland
New York Cancer and Blood Specialists

Port Jefferson Station, New York, 11776, United States
OU Health Stephenson Cancer Center

Oklahoma City, Oklahoma, 73104, United States
Ocala Oncology Center

Ocala, Florida, 34471, United States
Ospedale San Luca Luca

Lucca, 55100, Italy
Princess Alexandra Hospital

Woolloongabba, Queensland, 4102, Australia
Princess Margaret Hospital

Lai Chi Kok, Hong Kong
Providence Medical Foundation

Santa Rosa, California, 95403, United States
Queen Mary Hospital

Hong Kong, Hong Kong
Royal Marsden NHS Foundation Trust, Royal Marsden - Sutton

London, SM2 5PT, United Kingdom
Sanford Roger Maris Cancer Center

Fargo, North Dakota, 58122, United States
St. Vincent's Hospital Sydney

Darlinghurst, New South Wales, 2010, Australia
Stanford Cancer Institute

Palo Alto, California, 94305, United States
Technische Universitat Munchen (TUM) - Klinikum Rechts der Isar

Munich, 81675, Germany
Torrance Memorial Physician Network - Cancer Care Associates

Redondo Beach, California, 90277, United States
UCLA Hematology/Oncology

Los Angeles, California, 90095, United States
UZ Antwerpen

Edegem, 2650, Belgium
Unidade Local de Saude de Matosinhos EPE - Hospital Pedro Hispano SA

Matosinhos Municipality, 4464-513, Portugal
Universitaire Ziekenhuis Leuven

Leuven, 3000, Belgium
Universitatsmedizin Gottingen

GÃttingen, 37075, Germany
University Center and Blood Center,LLC.

Athens, Georgia, 30607, United States
University of the Sunshine Coast

Sippy Downs, Queensland, 4556, Australia
UniversitÃ¤tsklinikum Bonn, Medizinische Klinik und Poliklinik III

Bonn, 53127, Germany
Universitäres Krebszentrum Leipzig

Leipzig, 4103, Germany
Virginia Piper Cancer Center (Alliant Health

Minneapolis, Minnesota, 55407, United States
Washington University of Medicine- Siteman Cancer Center

St Louis, Missouri, 63110, United States
Wielkopolskie Centrum Onkologii im. Marii Sklodowskiej-Curie, Oddzial Onkologii Klinicznej i Immunookologii z Poddoddzialem Dziennym i Izba Przyjec

Poznan, 61-866, Poland
Wojewodzki Szpital Specjalistyczny w Siedlcach

Siedlce, 08-110, Poland
ZiekenhuisNetwerk Antwerpen (ZNA) - Stuivenberg

Antwerp, 2020, Belgium

Conditions

Explore the condition pages connected to this study.

HEAD AND NECK SQUAMOUS CELL CARCINOMA