New drug combo tested against aggressive breast cancer

NCT ID NCT04958785

Summary

This study tested whether adding an experimental drug called magrolimab to standard chemotherapy could better control advanced triple-negative breast cancer. Researchers enrolled 92 patients with cancer that couldn't be surgically removed and had spread locally or to other body parts. The trial aimed to find the safest dose and see if the combinations could slow cancer growth more effectively than standard treatments alone.

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Contacts and locations

Locations

  • Allina Health Cancer Institute

    Minneapolis, Minnesota, 55407, United States

  • Asan Medical Center

    Seoul, 5505, South Korea

  • Astera Cancer Care

    East Brunswick, New Jersey, 08816, United States

  • Ballarat Oncology & Haematology Services

    Wendouree, Victoria, 3355, Australia

  • Barwon Health- University Hospital Geelong

    Geelong, Victoria, '03220, Australia

  • Box Hill Hospital

    Box Hill, Victoria, 3128, Australia

  • Cairns and Hinterland Hospital and Health Service

    Cairns, Queensland, 4870, Australia

  • Cancer Research SA

    Adelaide, South Australia, 5000, Australia

  • Chang Gung Memorial Hospital, Linkou

    Guishan District, 131, Taiwan

  • Changhua Christian Hospital

    Changhua, 50006, Taiwan

  • Charleston Oncology

    Charleston, South Carolina, 29414, United States

  • Flinders Medical Centre

    Bedford Park, South Australia, 5042, Australia

  • Huntsman Cancer Institute, University of Utah

    Salt Lake City, Utah, 84112, United States

  • Kaohsiung Medical University Chung-Ho Memorial Hospital

    Sanmin District, 80778, Taiwan

  • Mayo Clinic

    Phoenix, Arizona, 85054, United States

  • Mayo Clinic

    Jacksonville, Florida, 32224, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • NYU Investigational Pharmacy, Laura & Isaac Perlmutter Cancer Center

    New York, New York, 10016, United States

  • National Cancer Center

    Goyang-si, 10408, South Korea

  • National Taiwan University Hospital

    Tapiei, Taiwan

  • Ochsner Clinic Foundation

    New Orleans, Louisiana, 70121, United States

  • Orchard Healthcare Research Inc

    Skokie, Illinois, 60077, United States

  • Peninsula Health

    Frankston, Victoria, 3199, Australia

  • Prince of Wales Hospital

    New Territories, Hong Kong

  • Princess Alexandra Hospital

    Woolloongabba, Queensland, 4102, Australia

  • Princess Margaret Hospital

    Kowloon, Hong Kong

  • Providence Medical Foundation

    Fullerton, California, 92835, United States

  • Providence Medical Foundation

    Santa Rosa, California, 95403, United States

  • Queen Mary Hospital

    Hong Kong, Hong Kong

  • Saint John's Cancer Institute

    Santa Monica, California, 90404, United States

  • Samsung Medical Center

    Gangnam-Gu, 06351, South Korea

  • Seoul National University Hospital

    Jongrogu, 110-744, South Korea

  • Severance Hospital Yonsei University Health System

    Seoul, 03722, South Korea

  • Southeastern Regional Medical Center, LLC

    Newnan, Georgia, 30265, United States

  • St Vincent's Hospital Melbourne

    Fitzroy, Victoria, 3065, Australia

  • Stony Brook University

    Stony Brook, New York, 11794, United States

  • Taipei Veterans General Hospital

    Beitou District, 11257, Taiwan

  • The Christie NHS Foundation Trust

    Manchester, M20 4BX, United Kingdom

  • University Cancer & Blood Center,LLC

    Athens, Georgia, 30607, United States

  • University College London

    London, WC1E 6BT, United Kingdom

  • University Hospitals of Leicester NHS Trust

    Leicester, LE1 5WW, United Kingdom

  • University of California San Francisco

    San Francisco, California, 94115, United States

  • University of the Sunshine Coast

    Sippy Downs, Queensland, 4556, Australia

  • Winship Cancer Institute Emory University

    Atlanta, Georgia, 30322, United States

  • Women's Cancer Care

    Fresno, California, 93710, United States

Conditions

Explore the condition pages connected to this study.