Ankle cartilage repair breakthrough? new phase 3 trial tests MACI against standard care
NCT ID NCT06915233
First seen Jan 06, 2026 · Last updated May 07, 2026 · Updated 19 times
Summary
This study tests a treatment called MACI for people with painful cartilage damage in the ankle. MACI uses a patient's own cartilage cells grown on a special membrane to repair the defect. The trial compares MACI to a standard procedure (bone marrow stimulation) in 309 adults aged 17 to 65. The goal is to see if MACI provides better pain relief and ankle function over two years.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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MedStar Georgetown University Hospital
RECRUITINGWashington D.C., District of Columbia, 20007, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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NextStage Clinical Research Houston - All American Orthopedic and Sports Medicine
RECRUITINGHouston, Texas, 77058, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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NextStage Clinical Research San Antonio - San Antonino Podiatry Associates
RECRUITINGSan Antonio, Texas, 78251, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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NextStage Clinical Research Wichita - Kansas Joint and Spine specialists
RECRUITINGWichita, Kansas, 67226, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Conditions
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